Issue 93, 2014
From the journal:

Chemical Communications

Dinuclear osmium(ii) probes for high-resolution visualisation of cellular DNA structure using electron microscopy†

Ashley Wragg,a   Martin R. Gill,b   Christopher J. Hill,b   Xiaodi Su,c   Anthony J. H. M. Meijer, ORCID logo a   Carl Smythe*b  and  Jim A. Thomas*a  

* Corresponding authors

a Department of Chemistry, University of Sheffield, Sheffield, S3 7HF UK
E-mail: james.thomas@sheffield.ac.uk

b Department of Biomedical Science, University of Sheffield, Sheffield, S3 7HF UK
E-mail: c.g.w.smythe@sheffield.ac.uk

c Institute of Material Research and Engineering, A*STAR (Agency for Science, Technology and Research), 3 Research Link, Singapore 117602

Abstract

Two dinuclear osmium polypyridyl complexes function as convenient, easy to handle TEM contrast agents and facilitate the high-resolution visualisation of intracellular structure, particularly sub-nuclear detail.

Graphical abstract: Dinuclear osmium(ii) probes for high-resolution visualisation of cellular DNA structure using electron microscopy

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Article information

DOI
https://doi.org/10.1039/C4CC05547K
Article type
Communication
Submitted
18 Jul 2014
Accepted
03 Sep 2014
First published
03 Sep 2014

Chem. Commun., 2014,50, 14494-14497

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Dinuclear osmium(II) probes for high-resolution visualisation of cellular DNA structure using electron microscopy

A. Wragg, M. R. Gill, C. J. Hill, X. Su, A. J. H. M. Meijer, C. Smythe and J. A. Thomas, Chem. Commun., 2014, 50, 14494 DOI: 10.1039/C4CC05547K

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