Issue 1, 2014

Rapid Wolff–Kishner reductions in a silicon carbide microreactor

Abstract

Wolff–Kishner reductions are performed in a novel silicon carbide microreactor. Greatly reduced reaction times and safer operation are achieved, giving high yields without requiring a large excess of hydrazine. The corrosion resistance of silicon carbide avoids the problematic reactor compatibility issues that arise when Wolff–Kishner reductions are done in glass or stainless steel reactors. With only nitrogen gas and water as by-products, this opens the possibility of performing selective, large scale ketone reductions without the generation of hazardous waste streams.

Graphical abstract: Rapid Wolff–Kishner reductions in a silicon carbide microreactor

Supplementary files

Article information

Article type
Paper
Submitted
16 Sep 2013
Accepted
05 Nov 2013
First published
12 Nov 2013

Green Chem., 2014,16, 176-180

Rapid Wolff–Kishner reductions in a silicon carbide microreactor

S. G. Newman, L. Gu, C. Lesniak, G. Victor, F. Meschke, L. Abahmane and K. F. Jensen, Green Chem., 2014, 16, 176 DOI: 10.1039/C3GC41942H

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