Issue 1, 2014
From the journal:

Lab on a Chip

A cell rolling cytometer reveals the correlation between mesenchymal stem cell dynamic adhesion and differentiation state†

Sungyoung Choi,ab   Oren Levy,c   Mónica B. Coelho,c   Joaquim M. S. Cabral,d   Jeffrey M. Karp*c  and  Rohit Karnik*a  

* Corresponding authors

a Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA 02139, USA
E-mail: karnik@mit.edu

b Department of Biomedical Engineering, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Gyeonggi-do, Yongin-si, Republic of Korea

c Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women's Hospital, Harvard Medical School, Harvard Stem Cell Institute, Harvard-MIT Division of Health Sciences and Technology, 65 Landsdowne St., Cambridge, MA 02139, USA
E-mail: jkarp@rics.bwh.harvard.edu

d Department of Bioengineering, Instituto Superior Técnico, Technical University of Lisbon, Av. Rovisco Pais, 1049-001 Lisboa, Portugal

Abstract

This communication presents quantitative studies of the dynamic adhesion behavior of mesenchymal stem cells (MSCs) enabled by the combination of cell-surface receptor–ligand interactions and three-dimensional hydrodynamic control by microtopography.

Graphical abstract: A cell rolling cytometer reveals the correlation between mesenchymal stem cell dynamic adhesion and differentiation state

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Article information

DOI
https://doi.org/10.1039/C3LC50923K
Article type
Communication
Submitted
07 Aug 2013
Accepted
02 Oct 2013
First published
21 Oct 2013

Lab Chip, 2014,14, 161-166

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A cell rolling cytometer reveals the correlation between mesenchymal stem cell dynamic adhesion and differentiation state

S. Choi, O. Levy, M. B. Coelho, J. M. S. Cabral, J. M. Karp and R. Karnik, Lab Chip, 2014, 14, 161 DOI: 10.1039/C3LC50923K

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