Efficient synthesis strategies by application of transition metal-catalyzed carbene/nitrene insertions into C–H bonds

Abstract

Covering: up to April 2013

Transition metal-catalyzed insertion of carbenes and nitrenes into C–H bonds has become a powerful tool for the construction of C–C and C–N bonds in the synthesis of complex natural products. In this Highlight, a selection of syntheses are detailed involving the implementation of C–H insertion reactions leading to strategies marked by improved efficiency.