The effect of aryl substitution on various aspects of the interconversion of ortho-hydroxychalcones and flavanones has been studied using multiple spectroscopic techniques. Derivatization of the core scaffold predictably alters the midpoint pH of this equilibration process suggesting its viability for application as a functional colorimetric molecular switch.
B. M. Muller, J. Mai, R. A. Yocum and M. J. Adler, Org. Biomol. Chem., 2014, 12, 5108 DOI: 10.1039/C4OB00398E
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