Issue 38, 2014

Diastereoselective synthesis of functionalized pyrrolidines through N-bromosuccinimide-induced aziridine ring expansion cascade of cinnamylaziridine

Abstract

An efficient aziridine ring expansion cascade of cinnamylaziridine has been developed. N-Bromosuccinimide was used as the promoter. The resulting functionalized pyrrolidines are the fundamental units of many useful molecules.

Graphical abstract: Diastereoselective synthesis of functionalized pyrrolidines through N-bromosuccinimide-induced aziridine ring expansion cascade of cinnamylaziridine

Supplementary files

Article information

Article type
Communication
Submitted
02 Jul 2014
Accepted
06 Aug 2014
First published
06 Aug 2014
This article is Open Access
Creative Commons BY-NC license

Org. Biomol. Chem., 2014,12, 7482-7485

Diastereoselective synthesis of functionalized pyrrolidines through N-bromosuccinimide-induced aziridine ring expansion cascade of cinnamylaziridine

J. Zhou and Y. Yeung, Org. Biomol. Chem., 2014, 12, 7482 DOI: 10.1039/C4OB01384K

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