Transporting platinum drugs from a copper chaperone to ATPase: the mechanistic implication of drug efflux mediated cisplatin resistance†
Abstract
Cisplatin transfers from Atox1 to ATPase, which could be associated with drug efflux from the cell.
* Corresponding authors
a
CAS Key Laboratory of Soft Matter Chemistry, CAS High Magnetic Field Laboratory, Department of Chemistry & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, 230026 Hefei, Anhui, China
E-mail:
liuyz@ustc.edu.cn
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Cisplatin transfers from Atox1 to ATPase, which could be associated with drug efflux from the cell.
D. Xu, Z. Xi, L. Zhao and Y. Liu, Inorg. Chem. Front., 2014, 1, 149 DOI: 10.1039/C3QI00068K
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