Issue 11, 2014
From the journal:

RSC Advances

Distribution of label free cationic polymer-coated gold nanorods in live macrophage cells reveals formation of groups of intracellular SERS signals of probe nanoparticles†

D. Pissuwan,*a   A. J. Hobro,a   N. Pavillona  and  N. I. Smith*a  

* Corresponding authors

a Biophotonics Laboratory, World Premier International Immunology Frontier Research Center, Osaka University, Osaka, Japan
E-mail: dakrong@ifrec.osaka-u.ac.jp, nsmith@ap.eng.osaka-u.ac.jp

Abstract

Gold nanorods coated with poly(diallydimethylammonium chloride) (PDAC-GNRs) were used to observe the distribution of surface-enhanced Raman signals in live cells and generate distinct groups of surface-enhanced Raman scattering (SERS) spectra in different regions of the cells. Spectra with unique features were clustered into sets of molecules in live murine macrophage cells (Raw 264.7). The distribution of biological substances detected by SERS signals of PDAC-GNRs is also discussed.

Graphical abstract: Distribution of label free cationic polymer-coated gold nanorods in live macrophage cells reveals formation of groups of intracellular SERS signals of probe nanoparticles

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Article information

DOI
https://doi.org/10.1039/C3RA45556D
Article type
Communication
Submitted
03 Oct 2013
Accepted
13 Dec 2013
First published
17 Dec 2013

RSC Adv., 2014,4, 5536-5541

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Distribution of label free cationic polymer-coated gold nanorods in live macrophage cells reveals formation of groups of intracellular SERS signals of probe nanoparticles

D. Pissuwan, A. J. Hobro, N. Pavillon and N. I. Smith, RSC Adv., 2014, 4, 5536 DOI: 10.1039/C3RA45556D

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