Issue 13, 2014

A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

Abstract

A BODIPY-based turn-on fluorescent probe 1 has been designed and synthesized for fluorescence detection of Cu2+ in aqueous media and imaging in living cells. The C[double bond, length as m-dash]N bonds are selectively hydrolyzed by the reaction with Cu2+ to generate formyl-BODIPY. The favorable features of probe 1 towards Cu2+ include significant fluorescence enhancement (over 290-fold), high selectivity and low detection limit (0.1 μM).

Graphical abstract: A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

Supplementary files

Article information

Article type
Communication
Submitted
29 Nov 2013
Accepted
02 Jan 2014
First published
06 Jan 2014

RSC Adv., 2014,4, 6691-6695

A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

J. Ye, J. Xu, H. Chen, Y. Bai, W. Zhang and W. He, RSC Adv., 2014, 4, 6691 DOI: 10.1039/C3RA47157H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements