Issue 98, 2014
From the journal:

RSC Advances

Arginine thioacid in synthesis of arginine conjugates and peptides†

Ravil N. Khaybullin,*a   Siva S. Panda,a   Saeid Mirzai,a   Ellen Toneff,a   Abdullah M. Asiri,bc   C. Dennis Hall*a  and  Alan R. Katritzkyab  

* Corresponding authors

a Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA
E-mail: ravilx84@gmail.com, charlesdennishall@gmail.com
Tel: +1-352-392-0554

b Center of Excellence for Advanced Material Research, King Abdulaziz University, Jeddah, Saudi Arabia

c Department of Chemistry, King Abdulaziz University, Jeddah, Saudi Arabia

Abstract

Protected arginine thioacid enables convenient N-acylation with no detectable racemization. We report efficient syntheses of potentially biologically active arginine conjugates and novel arginine-containing di-, tri- and tetrapeptides in good yields without loss of chiral integrity.

Graphical abstract: Arginine thioacid in synthesis of arginine conjugates and peptides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4RA04897K
Article type
Paper
Submitted
23 May 2014
Accepted
09 Oct 2014
First published
09 Oct 2014

RSC Adv., 2014,4, 55210-55216

Permissions

Request permissions

Arginine thioacid in synthesis of arginine conjugates and peptides

R. N. Khaybullin, S. S. Panda, S. Mirzai, E. Toneff, A. M. Asiri, C. D. Hall and A. R. Katritzky, RSC Adv., 2014, 4, 55210 DOI: 10.1039/C4RA04897K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements