Metal-free sequential reaction via a propargylation, annulation and isomerization sequence for the one-pot synthesis of 2,3-disubstituted benzofurans†
Abstract
A metal-free one-pot synthesis of 2,3-disubstituted benzofurans is described, which allows for the reactions to be performed under ambient conditions with readily accessible propargyl alcohols and general phenols, including phenols substituted with an electron withdrawing group or a nitrogen-containing group.