Issue 88, 2014

Pd-catalyzed oxidative C–H arylation of heterocycle embedded thiophene/furan with aryl boronic acid/ester

Abstract

Palladium catalyzed oxidative C–H arylation of heterocycle embedded thiophenes with aryl boronic acids is described. This method is found to display high C5-selectivity and thus enabled rapid access to 2,5-disubstituted thiophenes. Furan analogs also exhibited a similar selectivity.

Graphical abstract: Pd-catalyzed oxidative C–H arylation of heterocycle embedded thiophene/furan with aryl boronic acid/ester

Supplementary files

Article information

Article type
Paper
Submitted
21 Jun 2014
Accepted
18 Sep 2014
First published
19 Sep 2014

RSC Adv., 2014,4, 47697-47700

Pd-catalyzed oxidative C–H arylation of heterocycle embedded thiophene/furan with aryl boronic acid/ester

R. Srinivasan, R. Senthil Kumaran and N. S. Nagarajan, RSC Adv., 2014, 4, 47697 DOI: 10.1039/C4RA06055E

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