Issue 88, 2014

BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C–C bond formation

Abstract

A simple and efficient one pot protocol was developed for the synthesis of new structurally diverse 10-indolyldibenzo[b,f]azepine derivatives. The reaction involves Lewis-acid mediated ring expansion followed by C–C bond formation through nucleophilic addition of indole moiety.

Graphical abstract: BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C–C bond formation

Supplementary files

Article information

Article type
Paper
Submitted
15 Aug 2014
Accepted
22 Sep 2014
First published
23 Sep 2014

RSC Adv., 2014,4, 47833-47840

Author version available

BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C–C bond formation

T. Kotipalli, D. Janreddy, V. Kavala, C. Kuo, T. Kuo, M. Chen, C. He and C. Yao, RSC Adv., 2014, 4, 47833 DOI: 10.1039/C4RA08723B

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