Issue 104, 2014
From the journal:

RSC Advances

An oxidative cleavage-based ratiometric fluorescent probe for hypochlorous acid detection and imaging†

Fang Ma,ab   Mingtai Sun,b   Kui Zhang,b   Yajun Zhang,d   Houjuan Zhu,ab   Lijun Wu,d   Dejian Huang*c  and  Suhua Wang*ab  

* Corresponding authors

a Department of Chemistry, University of Science & Technology of China, Hefei, Anhui, China
E-mail: shwang@iim.ac.cn

b Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, Anhui, China

c Food Science and Technology Programme, Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
E-mail: chmhdj@nus.edu.sg

d Institute of Technical Biology & Agriculture Engineering, Chinese Academy of Sciences, Hefei, Anhui, China

Abstract

A new fluorescent molecule of an imidazole derivative was synthesized through simple cyclization of a hetero-aromatic compound and successfully applied for the rapid and ratiometric sensing of HOCl with high sensitivity and selectivity. It has also been demonstrated for the bioimaging of HOCl using A549 cells.

Graphical abstract: An oxidative cleavage-based ratiometric fluorescent probe for hypochlorous acid detection and imaging

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Article information

DOI
https://doi.org/10.1039/C4RA09611H
Article type
Communication
Submitted
02 Sep 2014
Accepted
03 Nov 2014
First published
05 Nov 2014

RSC Adv., 2014,4, 59961-59964

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An oxidative cleavage-based ratiometric fluorescent probe for hypochlorous acid detection and imaging

F. Ma, M. Sun, K. Zhang, Y. Zhang, H. Zhu, L. Wu, D. Huang and S. Wang, RSC Adv., 2014, 4, 59961 DOI: 10.1039/C4RA09611H

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