The synthesis of pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines via a one-pot three-component reaction by using benzene-1,2-dicarbaldehyde, trimethylsilylcyanide and various pyridin-2-amines in the presence of a catalytic amount of superparamagnetic nano-Fe3O4@SiO2 anchored sulfuric acid in ethanol in good-to-high yields is described.
![Graphical abstract: One-pot three-component synthesis of pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines using Fe3O4@SiO2–OSO3H as an efficient heterogeneous nanocatalyst](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C4RA10856F&imageInfo.ImageIdentifier.Year=2014)
A. Maleki, RSC Adv., 2014, 4, 64169 DOI: 10.1039/C4RA10856F
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