Issue 13, 2015
From the journal:

Analytical Methods

Tailor-made peptide sensor for detection of matrix metalloproteinase 2 in blood serum†

Huifeng Xu,ab   Hongzhi Ye,b   Lishuang Yu,b   Yuwu Chi,*a   Xianxiang Liu*b  and  Guonan Chena  

* Corresponding authors

a Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, P. R. China
E-mail: y.w.chi@fzu.edu.cn

b Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, P. R. China
E-mail: liuxianxiang@163.com

Abstract

We designed a simple and sensitive peptide electrochemical sensor for detection of MMP-2, with a detection limit of 0.3 ng mL−1. The sensor detected MMP-2 in a serum sample with satisfactory results. It was also used to assay an inhibitor of MMP-2.

Graphical abstract: Tailor-made peptide sensor for detection of matrix metalloproteinase 2 in blood serum

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Article information

DOI
https://doi.org/10.1039/C5AY00666J
Article type
Communication
Submitted
13 Mar 2015
Accepted
21 Apr 2015
First published
21 Apr 2015

Anal. Methods, 2015,7, 5371-5374

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Tailor-made peptide sensor for detection of matrix metalloproteinase 2 in blood serum

H. Xu, H. Ye, L. Yu, Y. Chi, X. Liu and G. Chen, Anal. Methods, 2015, 7, 5371 DOI: 10.1039/C5AY00666J

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