Issue 25, 2015
From the journal:

Chemical Communications

A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds†

Baptiste Thomas,ab   Michele Fiore,ab   Gour Chand Daskhan,ab   Nicolas Spinelliab  and  Olivier Renaudet*abc  

* Corresponding authors

a Univ. Grenoble Alpes, DCM, 38000 Grenoble, France
E-mail: olivier.renaudet@ujf-grenoble.fr
Fax: +33-456-520-805

b CNRS, DCM, 38000 Grenoble, France

c Institut Universitaire de France, 103 boulevard Saint-Michel, 75005 Paris, France

Abstract

Well-defined heterofunctionalized glycosylated scaffolds with unprecedented molecular combinations have been prepared using up to five different bioorthogonal ligations. This approach opens up chemical access to a diversity of biomolecular structures with high biological potential.

Graphical abstract: A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds

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Article information

DOI
https://doi.org/10.1039/C4CC05451B
Article type
Communication
Submitted
15 Jul 2014
Accepted
08 Aug 2014
First published
11 Aug 2014

Chem. Commun., 2015,51, 5436-5439

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A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds

B. Thomas, M. Fiore, G. C. Daskhan, N. Spinelli and O. Renaudet, Chem. Commun., 2015, 51, 5436 DOI: 10.1039/C4CC05451B

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