Issue 18, 2015
From the journal:

Chemical Communications

Probing structural changes of self assembled i-motif DNA†

Il Joon Lee,a   Sachin P. Patil,a   Karim Fhayli,a   Shahad Alsaiaria  and  Niveen M. Khashab*a  

* Corresponding authors

a Controlled Release and Delivery Lab (CRD), Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Makkah 23955-6900, Kingdom of Saudi Arabia
E-mail: niveen.khashab@kaust.edu.sa
Fax: +966-12-802-1172
Tel: +966-12-808-2410

Abstract

We report an i-motif structural probing system based on Thioflavin T (ThT) as a fluorescent sensor. This probe can discriminate the structural changes of RET and Rb i-motif sequences according to pH change.

Graphical abstract: Probing structural changes of self assembled i-motif DNA

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Article information

DOI
https://doi.org/10.1039/C4CC06824F
Article type
Communication
Submitted
29 Aug 2014
Accepted
16 Oct 2014
First published
16 Oct 2014

Chem. Commun., 2015,51, 3747-3749

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Probing structural changes of self assembled i-motif DNA

I. J. Lee, S. P. Patil, K. Fhayli, S. Alsaiari and N. M. Khashab, Chem. Commun., 2015, 51, 3747 DOI: 10.1039/C4CC06824F

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