Issue 15, 2015
From the journal:

Chemical Communications

A simple modular aptasensor platform utilizing cucurbit[7]uril and a ferrocene derivative as an ultrastable supramolecular linker†

Don-Wook Lee,‡ab   Kyeng Min Park,‡a   Bokyoung Gong,ac   Dinesh Shetty,a   Jayshree K. Khedkar,a   Kangkyun Baek,a   Jeehong Kim,ac   Sung Ho Ryu*bd  and  Kimoon Kim*abce  

* Corresponding authors

a Center for Self-assembly and Complexity, Institute for Basic Science (IBS), Pohang, Republic of Korea

b School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Republic of Korea
E-mail: kkim@postech.ac.kr

c Department of Chemistry, Pohang University of Science and Technology, Pohang, Republic of Korea

d Division of molecular and Life Science, Department of Life Science, Pohang University of Science and Technology, Pohang, Republic of Korea

e Division of Advanced Materials Science, Pohang University of Science and Technology, Pohang, Republic of Korea

Abstract

A simple modular aptamer-based sensor (aptasensor) platform was prepared by combining the merits of the rapid and efficient preparation of a self-assembled monolayer of cucurbit[7]uril (CB[7] SAM) and the strong and specific binding affinity of CB[7] to ferrocenemethylammonium (FA), as an ultrastable supramolecular linker, to immobilize aptamers on CB[7] SAM.

Graphical abstract: A simple modular aptasensor platform utilizing cucurbit[7]uril and a ferrocene derivative as an ultrastable supramolecular linker

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Article information

DOI
https://doi.org/10.1039/C4CC08027K
Article type
Communication
Submitted
10 Oct 2014
Accepted
05 Jan 2015
First published
05 Jan 2015
This article is Open Access
Creative Commons BY license

Chem. Commun., 2015,51, 3098-3101

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A simple modular aptasensor platform utilizing cucurbit[7]uril and a ferrocene derivative as an ultrastable supramolecular linker

D. Lee, K. M. Park, B. Gong, D. Shetty, J. K. Khedkar, K. Baek, J. Kim, S. H. Ryu and K. Kim, Chem. Commun., 2015, 51, 3098 DOI: 10.1039/C4CC08027K

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