A universal sensing platform based on the repair ligation-mediated light-producing DNA machine†
Abstract
The repair ligation-mediated light-producing DNA machine can produce light through transforming the repetitive DNA cleavage/ligation motions into optical energy without the requirement of either external reporting reagents or excitation light, and it can be applied for sensitive and selective detection of DNA, thrombin, adenosine, potassium ions (K+) and endonuclease even in human serum.