Issue 22, 2015
From the journal:

Chemical Communications

An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high sensitivity and selectivity†

Jing Wang,ab   Mengting Cheng,a   Zhen Zhang,c   Liangqia Guo,b   Qian Liu*a  and  Guibin Jianga  

* Corresponding authors

a State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
E-mail: qianliu@rcees.ac.cn

b Department of Chemistry, Fuzhou University, Fuzhou 350002, China

c School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China

Abstract

Graphene oxide nanoribbons (GONRs) were covalently functionalized with an antibody using polyethylene glycol (PEG) as a linker to produce a novel probe for surface enhanced laser desorption/ionization mass spectrometry (SELDI MS). This probe provides a highly sensitive and selective platform for enrichment and MS detection of small molecules in complex media.

Graphical abstract: An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high sensitivity and selectivity

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Article information

DOI
https://doi.org/10.1039/C4CC10401C
Article type
Communication
Submitted
30 Dec 2014
Accepted
10 Feb 2015
First published
10 Feb 2015

Chem. Commun., 2015,51, 4619-4622

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An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high sensitivity and selectivity

J. Wang, M. Cheng, Z. Zhang, L. Guo, Q. Liu and G. Jiang, Chem. Commun., 2015, 51, 4619 DOI: 10.1039/C4CC10401C

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