Issue 22, 2015
From the journal:

Chemical Communications

Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery†

Wen-Xing Gu,a   Qing-Lan Li,b   Hongguang Lu,a   Lei Fang,c   Qixian Chen,d   Ying-Wei Yang ORCID logo *b  and  Hui Gao*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, P. R. China
E-mail: hgao@tjut.edu.cn

b State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Jilin University, 2699 Qianjin Street, Changchun 130012, P. R. China
E-mail: ywyang@jlu.edu.cn

c Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, USA

d Department of Materials Engineering, Graduate School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

Abstract

Polymeric vesicles constructed from cyclodextrin- and azobenzene-grafted poly(glycidyl methacrylate)s showed excellent stability owing to the multiple host–guest complexation. Upon culturing in Na2S2O4-contained buffer solution, cargo-loaded vesicles disassembled, for potential applications in colon-specific drug delivery.

Graphical abstract: Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery

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Article information

DOI
https://doi.org/10.1039/C5CC00628G
Article type
Communication
Submitted
22 Jan 2015
Accepted
09 Feb 2015
First published
10 Feb 2015

Chem. Commun., 2015,51, 4715-4718

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Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery

W. Gu, Q. Li, H. Lu, L. Fang, Q. Chen, Y. Yang and H. Gao, Chem. Commun., 2015, 51, 4715 DOI: 10.1039/C5CC00628G

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