Issue 44, 2015

A triple-color fluorescent probe for multiple nuclease assays

Abstract

We develop a triple-color fluorescent probe which may function as a lab-on-a-DNA-molecule for simultaneous detection of multiple exonucleases/restriction endonucleases. This triple-color fluorescent probe can be further applied for the discrimination of seven exonucleases and four cell lines as well as the screening of various nuclease inhibitors.

Graphical abstract: A triple-color fluorescent probe for multiple nuclease assays

Supplementary files

Article information

Article type
Communication
Submitted
14 Mar 2015
Accepted
23 Apr 2015
First published
23 Apr 2015

Chem. Commun., 2015,51, 9121-9124

A triple-color fluorescent probe for multiple nuclease assays

Q. Xu, Y. Zhang and C. Zhang, Chem. Commun., 2015, 51, 9121 DOI: 10.1039/C5CC02177D

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