Issue 44, 2015
From the journal:

Chemical Communications

A bioresponsive controlled-release bioassay based on aptamer-gated Au nanocages and its application in living cells†

Wei Wang,*a   Chen Chen,‡a   Xiaoxiao Li,‡a   Shiying Wanga  and  Xiliang Luo*a  

* Corresponding authors

a Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
E-mail: wangwei9612@126.com, xiliangluo@hotmail.com
Fax: +86 532 84023927
Tel: +86 532 84022990

Abstract

A novel controlled-release bioassay for highly sensitive and selective detection of intracellular ATP was developed based on positive charge-modified Au nanocages capped with an aptamer molecular gate, and it was used successfully for fluorescence microscopy imaging of ATP in living cells.

Graphical abstract: A bioresponsive controlled-release bioassay based on aptamer-gated Au nanocages and its application in living cells

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Article information

DOI
https://doi.org/10.1039/C5CC02452H
Article type
Communication
Submitted
24 Mar 2015
Accepted
23 Apr 2015
First published
23 Apr 2015

Chem. Commun., 2015,51, 9109-9112

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A bioresponsive controlled-release bioassay based on aptamer-gated Au nanocages and its application in living cells

W. Wang, C. Chen, X. Li, S. Wang and X. Luo, Chem. Commun., 2015, 51, 9109 DOI: 10.1039/C5CC02452H

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