Issue 90, 2015
From the journal:

Chemical Communications

Visualizing virus particle mobility in liquid at the nanoscale†

A. Cameron Varano,a   Amina Rahimi,a   Madeline J. Dukes,b   Steven Poelzing,a   Sarah M. McDonalda  and  Deborah F. Kelly*a  

* Corresponding authors

a Virginia Tech Carilion Research Institute, Roanoke, VA 24016, USA
E-mail: debkelly@vt.edu
Fax: +1 540 985 3373
Tel: +1 540 526 2031

b Application Science, Protochips, Inc., Raleigh, NC 27606, USA

Abstract

Currently, there remains a critical need to develop real-time imaging resources for life sciences. Here, we demonstrate the use of high resolution in situ imaging to observe biological complexes in liquid at the nanoscale. Using a model virus system, we produced the first time-resolved videos of individual biological complexes moving in solution within an electron microscope.

Graphical abstract: Visualizing virus particle mobility in liquid at the nanoscale

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Article information

DOI
https://doi.org/10.1039/C5CC05744B
Article type
Communication
Submitted
10 Jul 2015
Accepted
04 Sep 2015
First published
04 Sep 2015
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2015,51, 16176-16179

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Visualizing virus particle mobility in liquid at the nanoscale

A. Cameron Varano, A. Rahimi, M. J. Dukes, S. Poelzing, S. M. McDonald and D. F. Kelly, Chem. Commun., 2015, 51, 16176 DOI: 10.1039/C5CC05744B

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