Aggregation-based detection of M. smegmatis using d-arabinose-functionalized fluorescent silica nanoparticles†
Abstract
Fluorescein-doped silica nanoparticles (FSNPs) functionalized with D-arabinose (Ara) showed strong interactions with Mycobacterium smegmatis (M. smegmatis) and caused the bacteria to aggregate. This aggregate formation was used as a means to detect M. smegmatis at the concentration of 104 CFU per mL.