Herein, a pH-sensitive probe has been designed based on DNA modified gold nanoparticles (AuNPs) for Raman/fluorescence dual-imaging of the intracellular pH distribution. In the acidic environment of cancer cells, the configuration change of DNA on the probe surface could turn “on” Raman/fluorescence signals simultaneously.
Y. Cao, R. Qian, D. Li and Y. Long, Chem. Commun., 2015, 51, 17584 DOI: 10.1039/C5CC07697H
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