Issue 2, 2015
From the journal:

Organic & Biomolecular Chemistry

Efficient merging of copper and photoredox catalysis for the asymmetric cross-dehydrogenative-coupling of alkynes and tetrahydroisoquinolines†

Inna Perepichka,a   Soumen Kundu,a   Zoë Hearnea  and  Chao-Jun Li*a  

* Corresponding authors

a Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, Quebec H3A 0B8, Canada
E-mail: cj.li@mcgill.ca

Abstract

A highly efficient catalytic asymmetric alkynylation of prochiral CH2 groups in tetrahydroisoquinoline was developed using copper catalyzed cross-dehydrogenative-coupling of sp3 and sp C–H bonds with the assistance of a photocatalyst and visible light.

Graphical abstract: Efficient merging of copper and photoredox catalysis for the asymmetric cross-dehydrogenative-coupling of alkynes and tetrahydroisoquinolines

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4OB02138J
Article type
Paper
Submitted
07 Oct 2014
Accepted
16 Oct 2014
First published
16 Oct 2014

Org. Biomol. Chem., 2015,13, 447-451

Author version available

Download author version (PDF)

Permissions

Request permissions

Efficient merging of copper and photoredox catalysis for the asymmetric cross-dehydrogenative-coupling of alkynes and tetrahydroisoquinolines

I. Perepichka, S. Kundu, Z. Hearne and C. Li, Org. Biomol. Chem., 2015, 13, 447 DOI: 10.1039/C4OB02138J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements