The N-heterocyclic carbene-catalyzed [3 + 3] cyclocondensation of bromoenals and hydrazones is developed to give the corresponding chiral 4,5-dihydropyridazones in good yields with excellent enantioselectivities.
![Graphical abstract: N-Heterocyclic carbene-catalyzed [3 + 3] cyclocondensation of bromoenals with hydrazones: highly enantioselective synthesis of dihydropyridazones](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C5OB01748C&imageInfo.ImageIdentifier.Year=2015)
C. Zhang, D. Wang, K. Chen and S. Ye, Org. Biomol. Chem., 2015, 13, 11255 DOI: 10.1039/C5OB01748C
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