Issue 11, 2015

Polyethylene glycol-400/H3PO2: an eco-friendly reductive system for the synthesis of selanylesters

Abstract

An alternative green method was described for the synthesis of selanylesters by reactions of acyl chlorides with arylselenols, generated in situ by reaction of diaryl diselenides with hypophosphorous acid (H3PO2) using polyethylene glycol-400 (PEG-400) as the solvent. These reactions proceeded efficiently at room temperature under N2 using a range of acyl chlorides and diaryl diselenides, both containing electron-withdrawing and electron-donating groups, affording the corresponding selanylesters in moderate to excellent yields. Additionally, PEG-400 can be recovered and directly reused for further reactions.

Graphical abstract: Polyethylene glycol-400/H3PO2: an eco-friendly reductive system for the synthesis of selanylesters

Supplementary files

Article information

Article type
Research Article
Submitted
13 Aug 2015
Accepted
19 Sep 2015
First published
21 Sep 2015

Org. Chem. Front., 2015,2, 1531-1535

Polyethylene glycol-400/H3PO2: an eco-friendly reductive system for the synthesis of selanylesters

G. Perin, M. B. Silveira, A. M. Barcellos, R. G. Jacob and D. Alves, Org. Chem. Front., 2015, 2, 1531 DOI: 10.1039/C5QO00256G

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