Issue 28, 2015
From the journal:

RSC Advances

Rhodamine derived colorimetric and fluorescence mercury(ii) chemodosimeter for human breast cancer cell (MCF7) imaging†

Babli Kumari,a   Sisir Lohar,a   Sangita Adhikari,a   Archya Sengupta, ORCID logo b   Ansuman Chattopadhyay,b   Paula Brandão,c   Vítor Félix*d  and  Debasis Das*a  

* Corresponding authors

a Department of Chemistry, The University of Burdwan, Burdwan, West Bengal, India
E-mail: ddas100in@yahoo.com
Fax: +91-342-2530452
Tel: +91-342-2533913

b Department of Zoology, Visva Bharati University, Santiniketan, West Bengal, India

c Departamento de Química, CICECO, Universidade de Aveiro, 3810-193 Aveiro, Portugal

d Departamento de Química, CICECO and Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, 3810-193 Aveiro, Portugal

Abstract

Condensation of rhodaminehydrazone with naphthalene-1-carboxaldehyde generates a colourless probe, RDHDNAP that can selectively detect Hg2+ through generation of a pink color along with significant fluorescence enhancement. The binding constant and lowest detection limit for Hg2+ are 2.0 × 105 M−1 and 3 × 10−7 M respectively. Hg2+ imaging in human breast cancer cells (MCF7) under a fluorescence microscope is achieved.

Graphical abstract: Rhodamine derived colorimetric and fluorescence mercury(ii) chemodosimeter for human breast cancer cell (MCF7) imaging

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Article information

DOI
https://doi.org/10.1039/C4RA14624G
Article type
Paper
Submitted
19 Nov 2014
Accepted
17 Feb 2015
First published
17 Feb 2015

RSC Adv., 2015,5, 21797-21802

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Rhodamine derived colorimetric and fluorescence mercury(II) chemodosimeter for human breast cancer cell (MCF7) imaging

B. Kumari, S. Lohar, S. Adhikari, A. Sengupta, A. Chattopadhyay, P. Brandão, Vítor Félix and D. Das, RSC Adv., 2015, 5, 21797 DOI: 10.1039/C4RA14624G

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