Issue 27, 2015
From the journal:

RSC Advances

Palladium-catalyzed synthesis of primary benzamides from aryl bromides via a cyanation and hydration sequence†

Muhammad Sharifabc  and  Xiao-Feng Wu*ab  

* Corresponding authors

a ZSTU-LIKAT Joint Laboratory of Catalysis, Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, Zhejiang Province, People's Republic of China
E-mail: xiao-feng.wu@catalysis.de

b Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock, Germany

c Department of Chemistry, Comsats Institute of Information Technology, Abbottabad, Pakistan

Abstract

An interesting and effective procedure for the synthesis of benzamides from aryl bromides has been developed. In the presence of a palladium catalyst, various primary benzamides have been produced in moderate to excellent yields in a one-pot one-step manner.

Graphical abstract: Palladium-catalyzed synthesis of primary benzamides from aryl bromides via a cyanation and hydration sequence

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Article information

DOI
https://doi.org/10.1039/C5RA00490J
Article type
Communication
Submitted
09 Jan 2015
Accepted
18 Feb 2015
First published
18 Feb 2015

RSC Adv., 2015,5, 21001-21004

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Palladium-catalyzed synthesis of primary benzamides from aryl bromides via a cyanation and hydration sequence

M. Sharif and X. Wu, RSC Adv., 2015, 5, 21001 DOI: 10.1039/C5RA00490J

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