Recent advances in multicomponent reactions involving carbohydrates

Abstract

Being an attractive class of naturally occurring molecules with fascinating properties sugars and their derivatives have wide applications in different fields especially in drug discovery. Due to their highly diverse nature they play various important key roles in biological systems. In terms of providing both desirable structural diversity and compound libraries, multicomponent reactions (MCRs) are most efficient strategies. MCRs are widely employed by chemists to generate sugar based derivatives with significantly extended variations having various benefits to society. The advances in the synthesis of structurally diversified sugar based derivatives through new MCRs of the previous decade are reviewed.