Issue 86, 2015
From the journal:

RSC Advances

Iridium-catalyzed methylation of indoles and pyrroles using methanol as feedstock†

Shu-Jie Chen,a   Guo-Ping Lua  and  Chun Cai*a  

* Corresponding authors

a School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China
E-mail: c.cai@mail.njust.edu.cn
Fax: +86-25-8431-5030
Tel: +86-25-8431-5514

Abstract

Iridium-catalyzed methylation of indoles and pyrroles using methanol as the methylating agent was achieved. This transformation takes place via a borrowing hydrogen methodology under an air atmosphere, which constitutes a direct route to 3-methyl-indoles and methyl-pyrroles.

Graphical abstract: Iridium-catalyzed methylation of indoles and pyrroles using methanol as feedstock

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Article information

DOI
https://doi.org/10.1039/C5RA15822B
Article type
Communication
Submitted
22 Jul 2015
Accepted
12 Aug 2015
First published
12 Aug 2015

RSC Adv., 2015,5, 70329-70332

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Iridium-catalyzed methylation of indoles and pyrroles using methanol as feedstock

S. Chen, G. Lu and C. Cai, RSC Adv., 2015, 5, 70329 DOI: 10.1039/C5RA15822B

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