Issue 90, 2015
From the journal:

RSC Advances

Synthesis of new chiral lactam-fused pyridine derivatives†

Tetsuya Sengoku,a   Yusuke Murata,b   Chihiro Suzuki,a   Masaki Takahashia  and  Hidemi Yoda*ab  

* Corresponding authors

a Department of Applied Chemistry, Faculty of Engineering, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
E-mail: tchyoda@ipc.shizuoka.ac.jp
Fax: +81 53 478 1150
Tel: +81 53 478 1150

b Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan

Abstract

New chiral C2-symmetric and unsymmetric lactam-fused pyridines have been synthesised in enantiomerically pure forms with satisfactory yields via an acid-promoted cyclisation of benzylidene-modified tetramic acids and various enamines.

Graphical abstract: Synthesis of new chiral lactam-fused pyridine derivatives

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Article information

DOI
https://doi.org/10.1039/C5RA16896A
Article type
Communication
Submitted
29 Jul 2015
Accepted
24 Aug 2015
First published
25 Aug 2015

RSC Adv., 2015,5, 73562-73565

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Synthesis of new chiral lactam-fused pyridine derivatives

T. Sengoku, Y. Murata, C. Suzuki, M. Takahashi and H. Yoda, RSC Adv., 2015, 5, 73562 DOI: 10.1039/C5RA16896A

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