Issue 123, 2015

Friedel–Crafts alkylation of heteroarenes and arenes with indolyl alcohols for construction of 3,3-disubstituted oxindoles

Abstract

An intriguing camphorsulfonic acid catalyzed Friedel–Crafts alkylation of heteroarenes and arenes with indolyl alcohols has been developed featuring mild reaction conditions, wide substrate scope and high yields. This reaction provides an efficient method to access biologically important heterocyclic oxindole derivatives.

Graphical abstract: Friedel–Crafts alkylation of heteroarenes and arenes with indolyl alcohols for construction of 3,3-disubstituted oxindoles

Supplementary files

Article information

Article type
Paper
Submitted
20 Oct 2015
Accepted
18 Nov 2015
First published
20 Nov 2015

RSC Adv., 2015,5, 101713-101717

Author version available

Friedel–Crafts alkylation of heteroarenes and arenes with indolyl alcohols for construction of 3,3-disubstituted oxindoles

X. Wang, J. Liu, L. Xu, Z. Hao, L. Wang and J. Xiao, RSC Adv., 2015, 5, 101713 DOI: 10.1039/C5RA21919A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements