Issue 15, 2015

A strategy for effective radioprotection by chitosan-based long-circulating nanocarriers

Abstract

We demonstrate a strategy for effective radioprotection by chitosan-based long-circulating nanocarriers with radio-protective agents. The stable encapsulation does not restrain its radioprotective capability, and exhibits prolonged retention time in blood with a half-life of ∼10 h, thereby showing more beneficial effects than the pure agent in therapeutic efficacy for irradiated mice.

Graphical abstract: A strategy for effective radioprotection by chitosan-based long-circulating nanocarriers

Supplementary files

Article information

Article type
Communication
Submitted
12 Jan 2015
Accepted
11 Feb 2015
First published
13 Feb 2015

J. Mater. Chem. B, 2015,3, 2931-2934

A strategy for effective radioprotection by chitosan-based long-circulating nanocarriers

Y. Zhou, S. Hua, J. Yu, P. Dong, F. Liu and D. Hua, J. Mater. Chem. B, 2015, 3, 2931 DOI: 10.1039/C5TB00063G

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