Issue 8, 2016

Emerging hydrogel designs for controlled protein delivery

Abstract

Hydrogels have evolved into indispensable biomaterials in the fields of drug delivery and regenerative medicine. This minireview aims to highlight the recent advances in the hydrogel design for controlled release of bioactive proteins. The latest developments of enzyme-responsive and externally regulated drug delivery systems are summarized. The design strategies and applications of phase-separated hydrogel systems are also described. We expect that these emerging approaches will enable expanded use of hydrogels in biomedicine and healthcare.

Graphical abstract: Emerging hydrogel designs for controlled protein delivery

Article information

Article type
Minireview
Submitted
12 May 2016
Accepted
21 Jun 2016
First published
04 Jul 2016

Biomater. Sci., 2016,4, 1184-1192

Emerging hydrogel designs for controlled protein delivery

K. H. Bae and M. Kurisawa, Biomater. Sci., 2016, 4, 1184 DOI: 10.1039/C6BM00330C

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