A very simple and time-saving cartridge-based drying technique for [18F]fluoride allows for an efficient [18F]FDG synthesis using protic solvents and high water content. This novel method has been adapted to a lab-on-chip synthesis platform mitigating the standard azeotropic drying process and demonstrating a proof of concept towards reduced hardware complexity for such systems.
![Graphical abstract: Azeotropic drying free [18F]FDG synthesis and its application to a lab-on-chip platform](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C5CC07106B&imageInfo.ImageIdentifier.Year=2016)
S. Lindner, C. Rensch, S. Neubaur, M. Neumeier, R. Salvamoser, V. Samper and P. Bartenstein, Chem. Commun., 2016, 52, 729 DOI: 10.1039/C5CC07106B
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