Issue 45, 2016
From the journal:

Chemical Communications

Ratiometric detection and imaging of endogenous hypochlorite in live cells and in vivo achieved by using an aggregation induced emission (AIE)-based nanoprobe†

Yong Huang,‡a   Peisheng Zhang,‡ab   Meng Gao,a   Fang Zeng,a   Anjun Qin,a   Shuizhu Wu*a  and  Ben Zhong Tanga  

* Corresponding authors

a College of Materials Science & Engineering, State Key Lab of Luminescent Materials & Devices, South China University of Technology, Guangzhou 510640, P. R. China
E-mail: shzhwu@scut.edu.cn
Fax: +86 20 22236363
Tel: +86 20 22236262

b Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education, Hunan Province College Key Laboratory of QSAR/QSPR, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, Hunan 411201, China

Abstract

An AIE-based fluorescent nanoprobe (MTPE-M) has been developed and used for ratiometric detection of hypochlorite with high selectivity and sensitivity. More importantly, its application in live cells and zebrafish for ratiometric imaging of endogenous ClO− has also been achieved.

Graphical abstract: Ratiometric detection and imaging of endogenous hypochlorite in live cells and in vivo achieved by using an aggregation induced emission (AIE)-based nanoprobe

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Article information

DOI
https://doi.org/10.1039/C6CC03415B
Article type
Communication
Submitted
23 Apr 2016
Accepted
10 May 2016
First published
10 May 2016

Chem. Commun., 2016,52, 7288-7291

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Ratiometric detection and imaging of endogenous hypochlorite in live cells and in vivo achieved by using an aggregation induced emission (AIE)-based nanoprobe

Y. Huang, P. Zhang, M. Gao, F. Zeng, A. Qin, S. Wu and B. Z. Tang, Chem. Commun., 2016, 52, 7288 DOI: 10.1039/C6CC03415B

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