Issue 83, 2016
From the journal:

Chemical Communications

Multi-color polymer pen lithography for oligonucleotide arrays†

R. Kumar,ab   S. Weigel,c   R. Meyer,c   C. M. Niemeyer,c   H. Fuchsab  and  M. Hirtz*a  

* Corresponding authors

a Institute of Nanotechnology (INT) & Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany
E-mail: michael.hirtz@kit.edu

b Physical Institute & Center for Nanotechnology (CeNTech), University of Münster, 48 Münster, Germany

c Institute of Biological Interfaces (IBG-1), Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany

Abstract

Multi-color patterning by polymer pen lithography (PPL) was used to fabricate covalently immobilized fluorophore and oligonucleotide arrays with up to five different components. The oligonucleotide arrays offer a virtually unlimited inventory of orthogonal binding tags for self-assembly of proteins as demonstrated by use of the arrays to monitor cell-protein interactions of MCF7 cells.

Graphical abstract: Multi-color polymer pen lithography for oligonucleotide arrays

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Article information

DOI
https://doi.org/10.1039/C6CC07087F
Article type
Communication
Submitted
29 Aug 2016
Accepted
22 Sep 2016
First published
22 Sep 2016

Chem. Commun., 2016,52, 12310-12313

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Multi-color polymer pen lithography for oligonucleotide arrays

R. Kumar, S. Weigel, R. Meyer, C. M. Niemeyer, H. Fuchs and M. Hirtz, Chem. Commun., 2016, 52, 12310 DOI: 10.1039/C6CC07087F

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