Issue 97, 2016
From the journal:

Chemical Communications

Two-photon fluorescence imaging of sialylated glycans in vivo based on a sialic acid imprinted conjugated polymer nanoprobe†

Wei Zhang,a   Junqing Kang,a   Ping Li,*a   Lu Liu,a   Hui Wanga  and  Bo Tang*a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Biomedical Sciences, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn

Abstract

We have designed and synthesized a sialic acid (SA)-imprinted conjugated polymer nanoprobe with two-photon fluorescence properties, which exhibits specific recognition ability to the target SA and has been used for monitoring sialylated glycan levels selectively in vivo.

Graphical abstract: Two-photon fluorescence imaging of sialylated glycans in vivo based on a sialic acid imprinted conjugated polymer nanoprobe

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Article information

DOI
https://doi.org/10.1039/C6CC08211D
Article type
Communication
Submitted
12 Oct 2016
Accepted
31 Oct 2016
First published
31 Oct 2016

Chem. Commun., 2016,52, 13991-13994

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Two-photon fluorescence imaging of sialylated glycans in vivo based on a sialic acid imprinted conjugated polymer nanoprobe

W. Zhang, J. Kang, P. Li, L. Liu, H. Wang and B. Tang, Chem. Commun., 2016, 52, 13991 DOI: 10.1039/C6CC08211D

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