The synergistic effect of cobalt on a Pd/Co catalyzed Suzuki–Miyaura cross-coupling in water

Abstract

This work introduces the new trimetallic complex CoPd₂(HBPDC)₂Cl₄·(H₂O)₄(H₂BPDC = 2,2′-bipyridine-4,4′-dicarboxylic acid) as a highly efficient and more cost-effective catalyst for a Suzuki–Miyaura reaction proceeding in water, without additives and under aerobic conditions. Catalytic studies revealed a synergistic Co–Pd cooperativity, fostered by ligation through H₂BPDC, and accounting for the superior performance of the heterobimetallic complex vs. its Co-free counterpart.