Issue 14, 2016
From the journal:

Lab on a Chip

Modification of PDMS to fabricate PLGA microparticles by a double emulsion method in a single microfluidic device

Leila Montazeri,ab   Shahin Bonakdar,c   Mojtaba Taghipour,d   Philippe Renaud*d  and  Hossein Baharvand*ae  

* Corresponding authors

a Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
E-mail: Baharvand@Royaninstitute.org

b Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran

c National Cell Bank, Pasteur Institute of Iran, Tehran, Iran

d Microsystems Laboratory, École Polytechnique Fédérale de Lausanne, EPFL-STI-IMT-LMIS4, Station 17, Lausanne, Switzerland
E-mail: Philippe.renaud@epfl.ch

e Department of Developmental Biology, University of Science and Culture, ACECR, Tehran, Iran

Abstract

We present an easy, durable method to generate a partially hydrophilic/hydrophobic poly(dimethylsiloxane) (PDMS) microfluidic device. The functionality of this device was assessed in a double flow focusing design to fabricate core–shell structured poly(lactic-co-glycolic acid) (PLGA) microparticles (MPs).

Graphical abstract: Modification of PDMS to fabricate PLGA microparticles by a double emulsion method in a single microfluidic device

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Article information

DOI
https://doi.org/10.1039/C6LC00437G
Article type
Communication
Submitted
01 Apr 2016
Accepted
08 Jun 2016
First published
08 Jun 2016

Lab Chip, 2016,16, 2596-2600

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Modification of PDMS to fabricate PLGA microparticles by a double emulsion method in a single microfluidic device

L. Montazeri, S. Bonakdar, M. Taghipour, P. Renaud and H. Baharvand, Lab Chip, 2016, 16, 2596 DOI: 10.1039/C6LC00437G

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