Issue 3, 2016
From the journal:

Natural Product Reports

The chemistry and biology of guanidine natural products

Roberto G. S. Berlinck*a  and  Stelamar Rommingera  

* Corresponding authors

a Instituto de Química de São Carlos, Universidade de São Paulo, CP 780, São Carlos, SP, Brazil
E-mail: rgsberlinck@iqsc.usp.br

Abstract

Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382

The present review discusses the isolation, structure determination, synthesis, biosynthesis and biological activities of secondary metabolites bearing a guanidine group. Topics include non-ribosomal peptides, alkaloids, guanidine-bearing terpenes, polyketides and shikimic acid derivatives from natural sources. A critical analysis of some yet underdeveloped aspects of guanidine metabolites is also presented.

Graphical abstract: The chemistry and biology of guanidine natural products

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Article information

DOI
https://doi.org/10.1039/C5NP00108K
Article type
Review Article
Submitted
01 Sep 2015
First published
22 Dec 2015

Nat. Prod. Rep., 2016,33, 456-490

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The chemistry and biology of guanidine natural products

R. G. S. Berlinck and S. Romminger, Nat. Prod. Rep., 2016, 33, 456 DOI: 10.1039/C5NP00108K

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