A unique annulation of 7-azaindoles with alkenyl esters to produce π-conjugated 7-azaindole derivatives

Abstract

Rhodium(III)-catalyzed N-directed ortho C–H activation and subsequent roll-over C–H activation represents an important strategy to synthesize fused polycyclic compounds. Herein, the novel methodology broadens the scope of the coupling partner to alkenes, which working smoothly with 7-azaindoles has been proven to be an efficient and atom-economical strategy to access complex π-conjugated 7-azaindole derivatives.