Issue 28, 2016

An aerobic Cu-mediated practical approach to aromatic nitriles using cyanide anions as the nitrogen source

Abstract

A Cu-mediated cyanation of aryl methyl ketones using cyanide anions as the nitrogen source was achieved to provide aromatic nitriles in moderate to good yields. The reaction tolerates a variety of synthetically important functional groups.

Graphical abstract: An aerobic Cu-mediated practical approach to aromatic nitriles using cyanide anions as the nitrogen source

Supplementary files

Article information

Article type
Communication
Submitted
12 Jun 2016
Accepted
14 Jun 2016
First published
23 Jun 2016

Org. Biomol. Chem., 2016,14, 6687-6690

An aerobic Cu-mediated practical approach to aromatic nitriles using cyanide anions as the nitrogen source

L. Gu, C. Jin, H. Zhang, J. Liu, Ganpeng Li and Z. Yang, Org. Biomol. Chem., 2016, 14, 6687 DOI: 10.1039/C6OB01269H

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