The γ-lactam moiety is present in a large number of natural and non-natural biologically active compounds. The range of biological activities covered by these compounds is very broad. Functionalized γ-lactams are thus of high interest and have great potential in medicinal chemistry. This review provides a description of the title compounds by focusing on their synthesis, natural sources and biological activities.
J. Caruano, G. G. Muccioli and R. Robiette, Org. Biomol. Chem., 2016, 14, 10134 DOI: 10.1039/C6OB01349J
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