Issue 5, 2016
From the journal:

Organic Chemistry Frontiers

Controlled TfOH- or AuCl-catalyzed cycloisomerization and tandem hydrolytic defluorination of 1,2-allenyl perfluoroalkyl ketones†

Can Xue,a   Xin Huang,a   Shangze Wu,a   Chunling Fu*a  and  Shengming Ma*a  

* Corresponding authors

a Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, Zhejiang, People's Republic of China
E-mail: masm@sioc.ac.cn

Abstract

An efficient TfOH- or AuCl-catalyzed cycloisomerization reaction of easily available n-perfluoroalkyl 1,2-allenyl ketones occurring smoothly to form 2-perfluoroalkyl furans has been reported. In the presence of TfOH and H2O, a corresponding tandem hydrolytic defluorination afforded multi-substituted furan-2-yl n-perfluoroalkyl ketones.

Graphical abstract: Controlled TfOH- or AuCl-catalyzed cycloisomerization and tandem hydrolytic defluorination of 1,2-allenyl perfluoroalkyl ketones

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6QO00001K
Article type
Research Article
Submitted
01 Jan 2016
Accepted
29 Mar 2016
First published
30 Mar 2016

Org. Chem. Front., 2016,3, 588-597

Permissions

Request permissions

Controlled TfOH- or AuCl-catalyzed cycloisomerization and tandem hydrolytic defluorination of 1,2-allenyl perfluoroalkyl ketones

C. Xue, X. Huang, S. Wu, C. Fu and S. Ma, Org. Chem. Front., 2016, 3, 588 DOI: 10.1039/C6QO00001K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements