Zheng-Li Hu, Chan Cao, Hui-Feng Wang and Bing-Yong Yan
RSC Adv., 2016,6, 105-108
DOI:
10.1039/C5RA20425A,
Communication
Herein an α-hemolysin nanopore was utilized to detect a DNA conjugate, where a propyl linker was attached to the 20-mer oligonucleotides at each end of an individual strand. The studies showed the alkyl linker produced a clear current change when translocating through the protein pore, which could be used to sense and identify small organic molecule at the single-molecule level.
